Review



ttp22  (Selleck Chemicals)


Bioz Verified Symbol Selleck Chemicals is a verified supplier
Bioz Manufacturer Symbol Selleck Chemicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Selleck Chemicals ttp22
    Ttp22, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/pm36222836-248-90-94
    Average 90 stars, based on 2 article reviews
    ttp22 - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    Expressing:

    Article Title: A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylation
    Article Snippet: The rest of the kinase inhibitors were purchased as indicated: Staurosporine (Sigma Aldrich, catalog # 569397), LJI308 (Sigma Aldrich, catalog # SML1788), Y-27632 (LC Laboratories, catalog # Y-5301), Gö 6976 (Sigma Aldrich, catalog # 365250), Gö 6983 (Sigma Aldrich, catalog # G1918), H-89 (Sigma Aldrich, catalog # B1427), D4476 (BioVision, catalog # 1770), KN-62 (Selleck Chemicals, catalog # S7422), KU-57788 (MedChem Express, catalog # HY-11006), Purvalanol B (AdipoGen Life Sciences, catalog # SYN-1070), KT-5823 (Cayman Chemicals, catalog # 10010965), PD0332991 (Sigma Aldrich, catalog # PZ0199), BMS-265246 (Selleck Chemicals, catalog # S2014), AT7519 (Selleck Chemicals, catalog # S1524), TTP22 (Selleck Chemicals, catalog # S6536) and Ellagic acid (Selleck Chemicals, catalog # S5516).

    Immunofluorescence:

    Article Title: A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylation
    Article Snippet: The rest of the kinase inhibitors were purchased as indicated: Staurosporine (Sigma Aldrich, catalog # 569397), LJI308 (Sigma Aldrich, catalog # SML1788), Y-27632 (LC Laboratories, catalog # Y-5301), Gö 6976 (Sigma Aldrich, catalog # 365250), Gö 6983 (Sigma Aldrich, catalog # G1918), H-89 (Sigma Aldrich, catalog # B1427), D4476 (BioVision, catalog # 1770), KN-62 (Selleck Chemicals, catalog # S7422), KU-57788 (MedChem Express, catalog # HY-11006), Purvalanol B (AdipoGen Life Sciences, catalog # SYN-1070), KT-5823 (Cayman Chemicals, catalog # 10010965), PD0332991 (Sigma Aldrich, catalog # PZ0199), BMS-265246 (Selleck Chemicals, catalog # S2014), AT7519 (Selleck Chemicals, catalog # S1524), TTP22 (Selleck Chemicals, catalog # S6536) and Ellagic acid (Selleck Chemicals, catalog # S5516).



    Similar Products

    ttp22  (MedChemExpress)
    91
    MedChemExpress ttp22
    Ttp22, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/us11666580-335-26-27
    Average 91 stars, based on 1 article reviews
    ttp22 - by Bioz Stars, 2026-09
    91/100 stars
    		  Buy from Supplier
    ttp22  (Selleck Chemicals)
    90
    Selleck Chemicals ttp22
    Ttp22, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/pm36222836-248-90-94
    Average 90 stars, based on 1 article reviews
    ttp22 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    drug ttp22 tocris tocris  (Tocris)
    92
    Tocris drug ttp22 tocris tocris
    Figure 4. Compounds promoting AT1 cell differentiation lead to concomitant loss of AT2 marker gene expression and WNT-dependent transcription. (A) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. <t>TTP22</t> and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. (B) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. (C) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). (B) Mean values are displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test. (C) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A- treated condition.
    Drug Ttp22 Tocris Tocris, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/10__7554_slash_elife__65811-141-19-21
    Average 92 stars, based on 1 article reviews
    drug ttp22 tocris tocris - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    ttp22  (Tocris)
    92
    Tocris ttp22
    ( A ) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. <t>TTP22</t> and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. ( B ) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. ( C ) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). ( B ) Mean values are displayed; error bars represent S.D.; p - values from one-way ANOVA, Tukey’s multiple comparisons test. ( C ) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A-treated condition. Figure 4—source data 1. Normalized expression values of AT2 cell markers, CK inhibitors vs. DMSO control. Normalized Axin2 expression values, CK inhibitors vs. DMSO control and related statistics. Raw luciferase data. Normalized luciferase values and related statistics.
    Ttp22, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/pmc08480975-44-4-6
    Average 92 stars, based on 1 article reviews
    ttp22 - by Bioz Stars, 2026-09
    92/100 stars
    		  Buy from Supplier
    ttp 22  (Bio-Techne corporation)
    90
    Bio-Techne corporation ttp 22
    ( A ) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. <t>TTP22</t> and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. ( B ) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. ( C ) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). ( B ) Mean values are displayed; error bars represent S.D.; p - values from one-way ANOVA, Tukey’s multiple comparisons test. ( C ) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A-treated condition. Figure 4—source data 1. Normalized expression values of AT2 cell markers, CK inhibitors vs. DMSO control. Normalized Axin2 expression values, CK inhibitors vs. DMSO control and related statistics. Raw luciferase data. Normalized luciferase values and related statistics.
    Ttp 22, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ttp22/TTP+22/bio-techne+corporation___4432
    Average 90 stars, based on 1 article reviews
    ttp 22 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Figure 4. Compounds promoting AT1 cell differentiation lead to concomitant loss of AT2 marker gene expression and WNT-dependent transcription. (A) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. TTP22 and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. (B) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. (C) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). (B) Mean values are displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test. (C) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A- treated condition.

    Journal: eLife

    Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures

    doi: 10.7554/elife.65811

    Figure Lengend Snippet: Figure 4. Compounds promoting AT1 cell differentiation lead to concomitant loss of AT2 marker gene expression and WNT-dependent transcription. (A) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. TTP22 and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. (B) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. (C) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). (B) Mean values are displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test. (C) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A- treated condition.

    Article Snippet: or resource Designation Source or reference Identifiers Additional information Chemical compound, drug Emodin Tocris Tocris:3811 (10 μM) Chemical compound, drug TTP22 Tocris Tocris:4432 (10 μM) Chemical compound, drug IC261 Sigma Sigma:I0658 (10 μM) Chemical compound, drug CX- 4945 Enzo Life Sciences Enzo Life Sciences: ENZ- CHM151 (10 μM) Chemical compound, drug DMAT Sigma Sigma:SML2044 (10 μM) Chemical compound, drug IWR- 1 Sigma Sigma:I0161 (10 μM) Commercial assay or kit Dual- Luciferase Reporter Assay System Promega Promega:E1910 Commercial assay or kit NucleoSpin RNA kit Macherey- Nagel MachereyNagel:740955.50 Commercial assay or kit Superscript III Reverse Transcriptase system Invitrogen Thermo Fisher Scientific:18080093 Commercial assay or kit DyNAmo ColorFlash SYBR green qPCR kit Thermo Scientific Thermo Fisher Scientific:F416XL Sequencebased reagent qPCR This paper Supplementary file 1 Software, algorithm Fiji/ImageJ 1.53 c Schindelin et al., 2012; doi:10.1038/nmeth.2019 RRID:SCR_002285 Software, algorithm GraphPad Prism 8 GraphPad RRID:SCR_002798 Continued

    Techniques: Cell Differentiation, Marker, Gene Expression, Expressing, Control, Inhibition, Luciferase

    ( A ) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. TTP22 and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. ( B ) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. ( C ) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). ( B ) Mean values are displayed; error bars represent S.D.; p - values from one-way ANOVA, Tukey’s multiple comparisons test. ( C ) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A-treated condition. Figure 4—source data 1. Normalized expression values of AT2 cell markers, CK inhibitors vs. DMSO control. Normalized Axin2 expression values, CK inhibitors vs. DMSO control and related statistics. Raw luciferase data. Normalized luciferase values and related statistics.

    Journal: eLife

    Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures

    doi: 10.7554/eLife.65811

    Figure Lengend Snippet: ( A ) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. TTP22 and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. ( B ) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. ( C ) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). ( B ) Mean values are displayed; error bars represent S.D.; p - values from one-way ANOVA, Tukey’s multiple comparisons test. ( C ) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A-treated condition. Figure 4—source data 1. Normalized expression values of AT2 cell markers, CK inhibitors vs. DMSO control. Normalized Axin2 expression values, CK inhibitors vs. DMSO control and related statistics. Raw luciferase data. Normalized luciferase values and related statistics.

    Article Snippet: Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 μM).

    Techniques: Expressing, Control, Inhibition, Luciferase

    Journal: eLife

    Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures

    doi: 10.7554/eLife.65811

    Figure Lengend Snippet:

    Article Snippet: Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 μM).

    Techniques: Recombinant, Transfection, Construct, Plasmid Preparation, Mutagenesis, Reporter Assay, Reverse Transcription, SYBR Green Assay, Sequencing, Software